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width="466"><table width="100%" height="387" border="0" cellpadding="4" cellspacing="0"> <tr> <td align="left" valign="top"><p class="teamtitle"><img src="../images/section_technology.jpg" width="458" height="100"><br> <p><font style="font-size: 9pt; color: black; font-family: tahoma; font-weight:bold">Advantages of BioMAP<sup>®</sup> Systems</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma; text-align: justify;">BioMAP<sup>®</sup> Systems are sensitive and powerful assays that allow scientists to obtain human pharmacological data at key decision points early in the R&D process. By enabling rapid determination of efficacy, side effects and mechanism of action of drug candidates, the BioMAP<sup>®</sup> Systems platform offers an innovative approach for the identification of both "first-in-class" and "best-in-class" drugs.</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;">BioMAP<sup>®</sup> systems use only human primary cells  ones taken directly from the body as opposed to being derived from cell lines  and cell combinations and culture conditions are carefully optimized so that cells behave as they would in the body. These systems provide the opportunity to sample new target and pathway space, and can be applied as a stand-alone platform for the identification of novel, innovative drug leads. The platform can also be used in conjunction with target-based and other screening approaches to select optimized drug candidates with enhanced biological features.</font></p> <table width="100%" border="0" cellpadding="5" cellspacing="1" bgcolor="#CCCCCC"> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: #57565B; font-family: tahoma; font-weight: bold">Features</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: #57565B; font-family: tahoma; font-weight: bold">Benefits</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Human primary cell-based assays</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Regulatory circuits and biological complexity intact</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Human disease models</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Clinically relevant pathways active; predictive of human biological response</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Automated assay systems</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Reproducibility within and between assays</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Proprietary database and computational platform</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Benchmarking vs. hundreds of known compounds and mechanisms</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Multiple, simultaneous target/pathway interrogation</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Broad coverage of human biology</font></p></td> </tr> <tr> <td width="206" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Secondary or off-target activity identification</font></p></td> <td width="229" valign="top" bgcolor="#FFFFFF"><p><font style="font-size: 9pt; color: black; font-family: tahoma;">Unlock hidden therapeutic value, reveal potential side-effects</font></p></td> </tr> </table> <br /> </td> </tr> </table></td> <td width="9" align="right"></td> </tr> </table></td> </tr> </table> </div> <!-------------------------------------GOOGLE TRACKING------------------------------> <script type="text/javascript"> var gaJsHost = (("https:" == document.location.protocol) ? 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