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Scientific Publications
| 2009 |
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Berg, E.L., J. Yang, J. Melrose, D. Nguyen, S. Privat, E. Rosler, E.J. Kunkel and S. Ekins. Chemical target and pathway toxicity mechanisms defined in primary human cell systems. J. Pharm. Tox. Methods, 2009 in press. |
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Houck, K.A., D.J. Dix, R.S. Judson, R.J. Kavlock, J. Yang and E.L. Berg. Profiling bioactivity of the ToxCast chemical library using BioMAP® primary human cell systems. J. Biomolecular Screening, 2009 in press. |
| 2008 |
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Berg, E.L. In the game. Drug Discovery & Development, 2008, 11:38-41. |
| 2006 |
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Kunkel EJ. Systems biology in drug discovery. Conference Proceedings, IEEE Engineering in Medicine and Biology Society. 2006, 1:37. |
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Berg EL, Kunkel EJ, Hytopoulos E, Plavec I. Characterization of compound mechanisms and secondary activities by BioMAP® analysis. Journal of Pharmacological and Toxicological Methods. 2006, 53:67-74. |
| 2004 |
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Butcher EC, Berg EL, Kunkel EJ. Systems biology in drug discovery. Nature Biotechnology. 2004 Oct;22(10):1253-9. PMID: 15470465 [pdf] |
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Eric J. Kunkel, Ivan Plavec, Dat Nguyen, Jennifer Melrose, Elen S. Rosler, Leon T. Kao, Yuker Wang, Evangelos Hytopoulos, Anthony C. Bishop, Raynard Bateman, Kevan M. Shokat, Eugene C. Butcher, Ellen L. Berg. Rapid Structure-Activity and Selectivity Analysis of Kinase Inhibitors by BioMAP® Analysis in Complex Human Primary Cell-Based Models. ASSAY and Drug Development Technologies. August 1, 2004, 2(4): 431-442. doi:10.1089/adt.2004.2.431. |
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Eric J. Kunkel, Marlene Dea, Allen Ebens, Evangelos Hytopoulos, Jennifer Melrose, Dat Nguyen, Ken S. Ota, Ivan Plavec, Yuker Wang, Susan R. Watson, Eugene C. Butcher, and Ellen L. Berg. "An integrative biology approach for analysis of drug action in models of human vascular inflammation." Journal of the Federation of American Societies for Experimental Biology. June 18, 2004. |
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Ivan Plavec, Ph.D., Ellen Berg, Ph.D.,Eugene Butcher, M.D. Method for analyzing signaling networks in complex cellular systems. Proceedings of the National Academy of Sciences. Feb. 3, 2004. (Vol. 101, no. 5 Pages 1223-1228). |
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