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<table width="100%" border="0" cellspacing="0" cellpadding="18"> <tr> <td width="39%" valign="top"><p><font style="font-size: 9pt; color: black; font-family: tahoma;"><strong>Contacts</strong> <br /><br /> Media<br /><br /> Shannon Richey<br /> Director of Marketing<br /> 313.263.0960&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <a title="mailto:shannon.richey@asterand.com" href="mailto:shannon.richey@asterand.com">shannon.richey@asterand.com</a></p> </td> </tr> <tr> <td valign="top"><font style="font-size: 9pt; color: black; font-family: tahoma;">Scientific<br /><br /> Ellen Berg, Ph.D.<br /> Chief Scientific Officer<br /> BioSeek, Inc.<br /> 650.888.0902<br /> <a title="mailto:ellen.berg@asterand.com" href="mailto:ellen.berg@asterand.com">ellen.berg@asterand.com</a> </font> </td> </tr> </table><p></p> <p><br> </p></td> <td width="5"></td> <td width="469"> <table width="100%" height="387" border="0" cellpadding="4" cellspacing="0"> <tr> <td align="left" valign="top"><p class="teamtitle"><img src="../../images/section_company.jpg" width="458" height="100"></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;"><strong>Press Release</strong></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;"><a href="../../news/press.htm">2009</a> | <a href="../../news/press08/press_08.htm">2008</a> | <a href="../../news/press07/press_07.htm">2007</a> | <a href="../../news/press06/press_06.htm">2006</a> and prior</p> <p><font style="font-size: 9pt; color: black; font-family: tahoma; font-weight:bold">May 20, 2008 - BioSeek to Collaborate with Merck Serono to Assess Potential Drug Candidates</p> <table width="100%" border="0" cellspacing="0" cellpadding="2"> <tr valign="top"> <td> <font style="font-size: 9pt; color: black; font-family: tahoma; text-align:justify;">BioSeek, Inc., a pioneer in the application of predictive human biology to drug discovery, announced today that it has entered into a collaboration agreement with Merck KGaA, Darmstadt, Germany acting for its division Merck Serono. Under the collaboration, BioSeek will apply its BioMAP® Systems to evaluate Merck Serono small molecule compounds and proteins across multiple therapeutic areas in support of target differentiation, lead selection, and nomination of candidates for preclinical development at Merck Serono. Financial details were not disclosed.</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;">"We are delighted that Merck Serono has chosen BioSeek as a partner to explore the utility of predictive human biology for the enhancement and acceleration of modern drug discovery, commented Michael C. Venuti, Ph.D., Chief Executive Officer of BioSeek. "BioMAP<sup>®</sup> Systems should provide an important value-added tool for the evaluation of compounds in Merck Serono's autoimmune and inflammatory disease programs, with additional applications in neurodegenerative diseases and oncology."</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;">"Our previous project with UCB clearly showed that, by combining proper study design and attention to detailed follow-up, the BioMAP<sup>®</sup> systems can be used to identify and advance promising molecules through preclinical evaluation in a way complementary to target-based drug discovery. By focusing on pharmacological outcome in a defined set of validated human cell-based screens, novel bioactivity can be detected, and anecdotally observed activity can be optimized. We look forward to working with UCB on these two major projects in the coming year," added Dr. Venuti.</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;">BioMAP<sup>®</sup> Systems are primary cell-based models of human disease biology, designed to replicate the intricate cell and pathway interactions as they are observed in vascular inflammation, cardiovascular and respiratory diseases, fibrosis and related clinical indications. Depending on their mechanism of action, compounds induce specific patterns of changes in these systems (BioMAP<sup>®</sup> profiles) that can be compared to a large number of reference profiles in the BioMAP<sup>®</sup> Database. Assessment with BioMAP<sup>®</sup> provides early insight into human pharmacological properties of compounds, including on- and off-target effects, dose responses, and the discrimination of closely related compounds.</font></p> <p><font style="font-size: 9pt; color: black; font-family: tahoma;"><strong>About BioSeek</strong><br /> BioSeek is improving the success rate of pharmaceutical research and development by integrating human biology from the earliest stages of drug discovery onward. The company's BioMAP<sup>®</sup> Systems incorporate predictive primary human cell-based disease models that generate uniquely informative activity profiles of each potential drug, assisting in the selection and development of new drug candidates. BioSeek is leveraging BioMAP<sup>®</sup> Systems technology in collaborations to enhance the productivity of its pharmaceutical partners' pipelines, and in the company's internal discovery programs.</font></p> </td> </tr> </table> <p>&nbsp;</p> </td> </tr> </table></td> <td width="10" align="right"></td> </tr> </table></td> </tr> </table> </div> <!-------------------------------------GOOGLE TRACKING------------------------------> <script type="text/javascript"> var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E")); </script> <script type="text/javascript"> try { var pageTracker = _gat._getTracker("UA-483128-3"); pageTracker._trackPageview(); } catch(err) {}</script> <!-----------------------------------------------------------------------------------> <map name="Map"> </map> </body> </html>